SREBP and MDT-15 protect C. elegans from glucose-induced accelerated aging by preventing accumulation of saturated fat

Glucose-rich diets shorten the life spans of various organisms. However, the metabolic processes involved in this phenomenon remain unknown. Here, we show that sterol regulatory element-binding protein (SREBP) and mediator-15 (MDT-15) prevent the life-shortening effects of a glucose-rich diet by reg...

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Foilsithe in:Genes Dev
Main Authors: Lee, Dongyeop, Jeong, Dae-Eun, Son, Heehwa G., Yamaoka, Yasuyo, Kim, Hyunmin, Seo, Keunhee, Khan, Abdul Aziz, Roh, Tae-Young, Moon, Dae Won, Lee, Youngsook, Lee, Seung-Jae V.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2015
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691952/
https://ncbi.nlm.nih.gov/pubmed/26637528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.266304.115
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