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p53 as an Effector or Inhibitor of Therapy Response

Although integrity of the p53 signaling pathway in a given tumor was expected to be a critical determinant of response to therapies, most clinical studies failed to link p53 status and treatment outcome. Here, we present two opposite situations: one in which p53 is an essential effector of cure by t...

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Foilsithe in:Cold Spring Harb Perspect Med
Main Authors: Ablain, Julien, Poirot, Brigitte, Esnault, Cécile, Lehmann-Che, Jacqueline, de Thé, Hugues
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cold Spring Harbor Laboratory Press 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691805/
https://ncbi.nlm.nih.gov/pubmed/26637438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026260
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