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A Novel Floating Controlled Release Drug Delivery System Prepared by Hot-Melt Extrusion

Floating dosage forms are an important formulation strategy for drugs with a narrow absorption window and low intestinal solubility, and for localized gastric treatment. Novel floating pellets were prepared using the hot-melt extrusion (HME) technology. Uniformly foamed strands were created by liqui...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Eur J Pharm Biopharm
Hauptverfasser: Vo, Anh Q., Feng, Xin, Morott, Joseph T., Pimparade, Manjeet B., Tiwari, Roshan V., Zhang, Feng, Repka, Michael A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691578/
https://ncbi.nlm.nih.gov/pubmed/26643801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2015.11.015
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