Investigation of Signal Transduction Routes within the Sensor/Transducer Protein BlaR1 of Staphylococcus aureus

The transmembrane antibiotic sensor/signal transducer protein BlaR1 is part of a cohort of proteins that confer β-lactam antibiotic resistance in methicillin-resistant Staphylococcus aureus (MRSA) (1–3). Specifically, BlaR1 regulates the inducible expression of β-lactamases that hydrolytically destr...

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Udgivet i:Biochemistry
Main Authors: Staude, Michael W., Frederick, Thomas E., Natarajan, Sivanandam V., Wilson, Brian D., Tanner, Carol E., Ruggiero, Steven T., Mobashery, Shahriar, Peng, Jeffrey W.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691190/
https://ncbi.nlm.nih.gov/pubmed/25658195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501463k
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