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The Intrinsic Dynamics and Unfolding Process of an Antibody Fab Fragment Revealed by Elastic Network Model

Antibodies have been increasingly used as pharmaceuticals in clinical treatment. Thermal stability and unfolding process are important properties that must be considered in antibody design. In this paper, the structure-encoded dynamical properties and the unfolding process of the Fab fragment of the...

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Detaylı Bibliyografya
Yayımlandı:Int J Mol Sci
Asıl Yazarlar: Su, Ji-Guo, Zhang, Xiao, Han, Xiao-Ming, Zhao, Shu-Xin, Li, Chun-Hua
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691140/
https://ncbi.nlm.nih.gov/pubmed/26690429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161226197
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