Different mechanisms of antibody-mediated neutralization of parvoviruses revealed using the Fab fragments of monoclonal antibodies

Antibody binding and neutralization are major host defenses against viruses, yet the mechanisms are often not well understood. Eight monoclonal antibodies and their Fab fragments were tested for neutralization of canine parvovirus and feline panleukopenia virus. All IgGs neutralized >90 percent o...

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Bibliographic Details
Main Authors: Nelson, Christian D.S., Palermo, Laura S., Hafenstein, Susan L., Parrish, Colin R.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1991280/
https://ncbi.nlm.nih.gov/pubmed/17217977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.11.032
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