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Different mechanisms of antibody-mediated neutralization of parvoviruses revealed using the Fab fragments of monoclonal antibodies

Antibody binding and neutralization are major host defenses against viruses, yet the mechanisms are often not well understood. Eight monoclonal antibodies and their Fab fragments were tested for neutralization of canine parvovirus and feline panleukopenia virus. All IgGs neutralized >90 percent o...

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Detalhes bibliográficos
Main Authors: Nelson, Christian D.S., Palermo, Laura S., Hafenstein, Susan L., Parrish, Colin R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1991280/
https://ncbi.nlm.nih.gov/pubmed/17217977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.11.032
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