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West Nile virus in complex with the Fab fragment of a neutralizing monoclonal antibody

Flaviviruses, such as West Nile virus (WNV), are significant human pathogens. The humoral immune response plays an important role in the control of flavivirus infection and disease. The structure of WNV complexed with the Fab fragment of the strongly neutralizing mAb E16 was determined to 14.5-Å res...

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Main Authors: Kaufmann, Bärbel, Nybakken, Grant E., Chipman, Paul R., Zhang, Wei, Diamond, Michael S., Fremont, Daved H., Kuhn, Richard J., Rossmann, Michael G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1567891/
https://ncbi.nlm.nih.gov/pubmed/16895988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603488103
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