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Does Lysosomial Acid Lipase Reduction Play a Role in Adult Non-Alcoholic Fatty Liver Disease?

Lysosomal Acid Lipase (LAL) is a key enzyme involved in lipid metabolism, responsible for hydrolysing the cholesteryl esters and triglycerides. Wolman Disease represents the early onset phenotype of LAL deficiency rapidly leading to death. Cholesterol Ester Storage Disease is a late onset phenotype...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Baratta, Francesco, Pastori, Daniele, Polimeni, Licia, Tozzi, Giulia, Violi, Francesco, Angelico, Francesco, Del Ben, Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691032/
https://ncbi.nlm.nih.gov/pubmed/26602919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161226085
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