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Reduced Lysosomal Acid Lipase Activity in Adult Patients With Non-alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease (NAFLD) is characterized by intra-hepatic fat accumulation and mechanisms involved in its pathogenesis are not fully explained. Lysosomal Acid Lipase (LAL) is a key enzyme in lipid metabolism. We investigated its activity in patients with fatty liver. LAL activity (...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Baratta, Francesco, Pastori, Daniele, Del Ben, Maria, Polimeni, Licia, Labbadia, Giancarlo, Di Santo, Serena, Piemonte, Fiorella, Tozzi, Giulia, Violi, Francesco, Angelico, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534687/
https://ncbi.nlm.nih.gov/pubmed/26288848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.05.018
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