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Tyrosine modification increases the affinity of gastrin for ferric ions

The peptide hormone gastrin(17), which occurs naturally in both tyrosine sulphated and unsulphated forms, binds two ferric ions with pM affinities. The aim of this study was to investigate the hypothesis that sulphation or phosphorylation of gastrin(17) altered ferric ion binding, and/or affinity fo...

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Detalhes bibliográficos
Publicado no:Springerplus
Main Authors: Baldwin, Graham S., Sims, Ioulia
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690827/
https://ncbi.nlm.nih.gov/pubmed/26722635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-015-1622-2
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