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High Affinity Binding of Indium and Ruthenium Ions by Gastrins

The peptide hormone gastrin binds two ferric ions with high affinity, and iron binding is essential for the biological activity of non-amidated forms of the hormone. Since gastrins act as growth factors in gastrointestinal cancers, and as peptides labelled with Ga and In isotopes are increasingly us...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Baldwin, Graham S., George, Graham N., Pushie, M. Jake
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601796/
https://ncbi.nlm.nih.gov/pubmed/26457677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140126
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