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Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures
Diverse repertoires of antigen-receptor genes that result from combinatorial splicing of coding segments by V(D)J recombination are hallmarks of vertebrate immunity. The (RAG1-RAG2)(2) recombinase (RAG) recognizes recombination signal sequences (RSSs) containing a heptamer, a spacer of 12 or 23 base...
Shranjeno v:
| izdano v: | Cell |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4690471/ https://ncbi.nlm.nih.gov/pubmed/26548953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.10.055 |
| Oznake: |
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