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Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures
Diverse repertoires of antigen-receptor genes that result from combinatorial splicing of coding segments by V(D)J recombination are hallmarks of vertebrate immunity. The (RAG1-RAG2)(2) recombinase (RAG) recognizes recombination signal sequences (RSSs) containing a heptamer, a spacer of 12 or 23 base...
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| Publicat a: | Cell |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4690471/ https://ncbi.nlm.nih.gov/pubmed/26548953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.10.055 |
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