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FGF/MAPK signaling sets the switching threshold of a bistable circuit controlling cell fate decisions in embryonic stem cells

Intracellular transcriptional regulators and extracellular signaling pathways together regulate the allocation of cell fates during development, but how their molecular activities are integrated to establish the correct proportions of cells with particular fates is not known. Here we study this ques...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Development
मुख्य लेखकों: Schröter, Christian, Rué, Pau, Mackenzie, Jonathan Peter, Martinez Arias, Alfonso
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Company of Biologists 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689219/
https://ncbi.nlm.nih.gov/pubmed/26511924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.127530
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