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In silico analysis of calcium binding pocket of perforin like protein 1: insights into the regulation of pore formation

Plasmodium falciparum perforin like proteins (PfPLPs) are an important arsenal for the entry and exit of malaria parasites. These proteins bind and oligomerize on the membrane in calcium dependent manner and form an open pore. The calcium dependent pore forming activity of PLPs is usually conferred...

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Dades bibliogràfiques
Publicat a:Syst Synth Biol
Autors principals: Garg, Swati, Sharma, Vijeta, Ramu, Dandugudumula, Singh, Shailja
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688409/
https://ncbi.nlm.nih.gov/pubmed/26702304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11693-015-9166-x
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