Llwytho...
PTEN is required to maintain luminal epithelial homeostasis and integrity in the adult mammary gland
In the mammary gland, PTEN loss in luminal and basal epithelial cells results in differentiation defects and enhanced proliferation, leading to the formation of tumors with basal epithelial characteristics. In breast cancer, PTEN loss is associated with a hormone receptor-negative, basal-like subtyp...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Dev Biol |
|---|---|
| Prif Awduron: | , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2015
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4688181/ https://ncbi.nlm.nih.gov/pubmed/26526198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2015.10.023 |
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