VANGL2 regulates luminal epithelial organization and cell turnover in the mammary gland

The VANGL family of planar cell polarity proteins is implicated in breast cancer however its function in mammary gland biology is unknown. Here, we utilized a panel of Vang1 and Vangl2 mouse alleles to examine the requirement of VANGL family members in the murine mammary gland. We show that Vang1CKO...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Smith, Prestina, Godde, Nathan, Rubio, Stefany, Tekeste, Melawit, Vladar, Eszter K., Axelrod, Jeffrey D., Henderson, Deborah J., Milgrom-Hoffman, Michal, Humbert, Patrick O., Hinck, Lindsay
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506599/
https://ncbi.nlm.nih.gov/pubmed/31068622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43444-8
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