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Inhibition of Histone Deacetylase 6 Restores Innate Immune Cells in Bone Marrow in a Lethal Septic Model
BACKGROUND: We have previously demonstrated that Tubastatin A, a selective inhibitor of histone deacetylase (HDAC) 6, improves survival, and increases circulating monocyte count and bacterial clearance in a lethal model of cecal ligation and puncture (CLP) in mice. The aim of the present study was t...
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| Publicat a: | J Trauma Acute Care Surg |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4688101/ https://ncbi.nlm.nih.gov/pubmed/26491797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000000897 |
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