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Inhibition of Histone Deacetylase 6 Restores Innate Immune Cells in Bone Marrow in a Lethal Septic Model

BACKGROUND: We have previously demonstrated that Tubastatin A, a selective inhibitor of histone deacetylase (HDAC) 6, improves survival, and increases circulating monocyte count and bacterial clearance in a lethal model of cecal ligation and puncture (CLP) in mice. The aim of the present study was t...

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Detaylı Bibliyografya
Yayımlandı:J Trauma Acute Care Surg
Asıl Yazarlar: Zhao, Ting, Li, Yongqing, Liu, Baoling, Pan, Baihong, Cheng, Xin, Georgoff, Patrick, Alam, Hasan B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688101/
https://ncbi.nlm.nih.gov/pubmed/26491797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000000897
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