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The sGC stimulator riociguat inhibits platelet function in washed platelets but not in whole blood
BACKGROUND AND PURPOSE: Stimulation of soluble guanylyl cyclase (sGC) is a valuable therapeutic strategy for the treatment of several cardiovascular diseases. The sGC stimulator riociguat has been approved for the treatment of two forms of pulmonary hypertension. Platelets contain large amounts of s...
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| Gepubliceerd in: | Br J Pharmacol |
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| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley and Sons Inc.
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4687809/ https://ncbi.nlm.nih.gov/pubmed/26282717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13286 |
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