A carregar...
tRNA processing defects induce replication stress and Chk2‐dependent disruption of piRNA transcription
RNase P is a conserved endonuclease that processes the 5′ trailer of tRNA precursors. We have isolated mutations in Rpp30, a subunit of RNase P, and find that these induce complete sterility in Drosophila females. Here, we show that sterility is not due to a shortage of mature tRNAs, but that atroph...
Na minha lista:
| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4687792/ https://ncbi.nlm.nih.gov/pubmed/26471728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201591006 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|