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Paramutation in Drosophila Requires Both Nuclear and Cytoplasmic Actors of the piRNA Pathway and Induces Cis-spreading of piRNA Production

Transposable element activity is repressed in the germline in animals by PIWI-interacting RNAs (piRNAs), a class of small RNAs produced by genomic loci mostly composed of TE sequences. The mechanism of induction of piRNA production by these loci is still enigmatic. We have shown that, in Drosophila...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Hermant, Catherine, Boivin, Antoine, Teysset, Laure, Delmarre, Valérie, Asif-Laidin, Amna, van den Beek, Marius, Antoniewski, Christophe, Ronsseray, Stéphane
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4676525/
https://ncbi.nlm.nih.gov/pubmed/26482790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.180307
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