Identifying an ovarian cancer cell hierarchy regulated by bone morphogenetic protein 2

Whether human cancer follows a hierarchical or stochastic model of differentiation is controversial. Furthermore, the factors that regulate cancer stem-like cell (CSC) differentiation potential are largely unknown. We used a novel microfluidic single-cell culture method to directly observe the diffe...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Choi, Yun-Jung, Ingram, Patrick N., Yang, Kun, Coffman, Lan, Iyengar, Mangala, Bai, Shoumei, Thomas, Dafydd G., Yoon, Euisik, Buckanovich, Ronald J.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
PNAS Plus
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687560/
https://ncbi.nlm.nih.gov/pubmed/26621735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1507899112
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