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Identifying an ovarian cancer cell hierarchy regulated by bone morphogenetic protein 2
Whether human cancer follows a hierarchical or stochastic model of differentiation is controversial. Furthermore, the factors that regulate cancer stem-like cell (CSC) differentiation potential are largely unknown. We used a novel microfluidic single-cell culture method to directly observe the diffe...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4687560/ https://ncbi.nlm.nih.gov/pubmed/26621735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1507899112 |
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