Similar striatal gene expression profiles in the striatum of the YAC128 and HdhQ150 mouse models of Huntington’s disease are not reflected in mutant Huntingtin inclusion prevalence

BACKGROUND: The YAC128 model of Huntington’s disease (HD) shows substantial deficits in motor, learning and memory tasks and alterations in its transcriptional profile. We examined the changes in the transcriptional profile in the YAC128 mouse model of HD at 6, 12 and 18 months and compared these wi...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Bayram-Weston, Zubeyde, Stone, Timothy C., Giles, Peter, Elliston, Linda, Janghra, Nari, Higgs, Gemma V., Holmans, Peter A., Dunnett, Stephen B., Brooks, Simon P., Jones, Lesley
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687121/
https://ncbi.nlm.nih.gov/pubmed/26691352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2251-4
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