Topographic Mapping of the Synaptic Cleft into Adhesive Nanodomains

The cleft is an integral part of synapses, yet its macromolecular organization remains unclear. We here show that the cleft of excitatory synapses exhibits a distinct density profile as measured by cryo-electron tomography (cryo-ET). Aiming for molecular insights, we analyzed the synapse-organizing...

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Pubblicato in:Neuron
Autori principali: de Arce, Karen Perez, Schrod, Nikolas, Metzbower, Sarah W. R., Allgeyer, Edward, Kong, Geoffrey K.-W., Tang, Aihui, Krupp, Alexander J., Stein, Valentin, Liu, Xinran, Bewersdorf, Jörg, Blanpied, Thomas A., Lucic, Vladan, Biederer, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687029/
https://ncbi.nlm.nih.gov/pubmed/26687224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.11.011
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