Topographic Mapping of the Synaptic Cleft into Adhesive Nanodomains

The cleft is an integral part of synapses, yet its macromolecular organization remains unclear. We here show that the cleft of excitatory synapses exhibits a distinct density profile as measured by cryo-electron tomography (cryo-ET). Aiming for molecular insights, we analyzed the synapse-organizing...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: de Arce, Karen Perez, Schrod, Nikolas, Metzbower, Sarah W. R., Allgeyer, Edward, Kong, Geoffrey K.-W., Tang, Aihui, Krupp, Alexander J., Stein, Valentin, Liu, Xinran, Bewersdorf, Jörg, Blanpied, Thomas A., Lucic, Vladan, Biederer, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687029/
https://ncbi.nlm.nih.gov/pubmed/26687224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.11.011
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