Topographic Mapping of the Synaptic Cleft into Adhesive Nanodomains

The cleft is an integral part of synapses, yet its macromolecular organization remains unclear. We here show that the cleft of excitatory synapses exhibits a distinct density profile as measured by cryo-electron tomography (cryo-ET). Aiming for molecular insights, we analyzed the synapse-organizing...

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Vydáno v:Neuron
Hlavní autoři: de Arce, Karen Perez, Schrod, Nikolas, Metzbower, Sarah W. R., Allgeyer, Edward, Kong, Geoffrey K.-W., Tang, Aihui, Krupp, Alexander J., Stein, Valentin, Liu, Xinran, Bewersdorf, Jörg, Blanpied, Thomas A., Lucic, Vladan, Biederer, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687029/
https://ncbi.nlm.nih.gov/pubmed/26687224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.11.011
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