Loss of expression of transforming growth factor beta in skin and skin tumors is associated with hyperproliferation and a high risk for malignant conversion.

Mouse skin carcinomas arise from a small subpopulation of benign papillomas with an increased risk of malignant conversion. These papillomas arise with limited stimulation by tumor promoters, appear rapidly, and do not regress, suggesting that they differ in growth properties from the majority of be...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Glick, A B, Kulkarni, A B, Tennenbaum, T, Hennings, H, Flanders, K C, O'Reilly, M, Sporn, M B, Karlsson, S, Yuspa, S H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46870/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7687059/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.13.6076
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