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Kinetochore–microtubule attachment is sufficient to satisfy the human spindle assembly checkpoint

The spindle assembly checkpoint (SAC) is a genome surveillance mechanism that protects against aneuploidization. Despite profound progress on understanding mechanisms of its activation, it remains unknown what aspect of chromosome–spindle interactions is monitored by the SAC: kinetochore–microtubule...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Etemad, Banafsheh, Kuijt, Timo E. F., Kops, Geert J. P. L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686852/
https://ncbi.nlm.nih.gov/pubmed/26621779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9987
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