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QLT091001, a 9-cis-Retinal Analog, Is Well-Tolerated by Retinas of Mice with Impaired Visual Cycles
PURPOSE. Investigate whether retinas of mice with impaired retinal cycles exposed to light or kept in the dark tolerate prolonged high-dose administration of QLT091001, which contains as an active ingredient, the 9-cis-retinal precursor, 9-cis-retinyl acetate. METHODS. Four- to six-week-old Lrat(−/−...
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| Publicat a: | Invest Ophthalmol Vis Sci |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Association for Research in Vision and Ophthalmology
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4686220/ https://ncbi.nlm.nih.gov/pubmed/23249702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-11152 |
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