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Reduced Levels of Proteasome Products in a Mouse Striatal Cell Model of Huntington’s Disease
Huntington’s disease is the result of a long polyglutamine tract in the gene encoding huntingtin protein, which in turn causes a large number of cellular changes and ultimately results in neurodegeneration of striatal neurons. Although many theories have been proposed, the precise mechanism by which...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4686214/ https://ncbi.nlm.nih.gov/pubmed/26691307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145333 |
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