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The Icelandic founder mutation BRCA2 999del5: analysis of expression

INTRODUCTION: A founder mutation in the BRCA2 gene (BRCA2 999del5) accounts for 7–8% of female breast cancers and for 40% of male breast cancers in Iceland. If expressed, the mutant gene would encode a protein consisting of the first 256 amino acids of the BRCA2 protein. The purpose of this study wa...

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Main Authors: Mikaelsdottir, Evgenia K, Valgeirsdottir, Sigridur, Eyfjord, Jorunn E, Rafnar, Thorunn
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC468616/
https://ncbi.nlm.nih.gov/pubmed/15217494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr785
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