Generation and Characterization of Rat Monoclonal Antibodies Against Epidermal Growth Factor Receptor

Overexpression of the epidermal growth factor receptor (EGFR) gene and dysregulation of EGFR signaling are observed in various cancer cells, and EGFR is a validated target for cancer therapy. In the present study, we report on the generation of two rat anti-EGFR antibodies (clones 2C2D3 and 4H7F4) b...

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Bibliographische Detailangaben
Veröffentlicht in:Monoclon Antib Immunodiagn Immunother
Hauptverfasser: Osaki, Tomohiro, Wang, Cai-Xia, Tachibana, Taro, Azuma, Masayuki, Kitamura, Masaya, Nakanishi, Takeshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2015
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685498/
https://ncbi.nlm.nih.gov/pubmed/26683181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/mab.2015.0034
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