Generation and Characterization of Rat Monoclonal Antibodies Against Epidermal Growth Factor Receptor

Overexpression of the epidermal growth factor receptor (EGFR) gene and dysregulation of EGFR signaling are observed in various cancer cells, and EGFR is a validated target for cancer therapy. In the present study, we report on the generation of two rat anti-EGFR antibodies (clones 2C2D3 and 4H7F4) b...

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Bibliografiske detaljer
Udgivet i:Monoclon Antib Immunodiagn Immunother
Main Authors: Osaki, Tomohiro, Wang, Cai-Xia, Tachibana, Taro, Azuma, Masayuki, Kitamura, Masaya, Nakanishi, Takeshi
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2015
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685498/
https://ncbi.nlm.nih.gov/pubmed/26683181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/mab.2015.0034
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