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Generation and Characterization of Rat Monoclonal Antibodies Against Epidermal Growth Factor Receptor

Overexpression of the epidermal growth factor receptor (EGFR) gene and dysregulation of EGFR signaling are observed in various cancer cells, and EGFR is a validated target for cancer therapy. In the present study, we report on the generation of two rat anti-EGFR antibodies (clones 2C2D3 and 4H7F4) b...

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Bibliografische gegevens
Gepubliceerd in:Monoclon Antib Immunodiagn Immunother
Hoofdauteurs: Osaki, Tomohiro, Wang, Cai-Xia, Tachibana, Taro, Azuma, Masayuki, Kitamura, Masaya, Nakanishi, Takeshi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Mary Ann Liebert, Inc. 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685498/
https://ncbi.nlm.nih.gov/pubmed/26683181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/mab.2015.0034
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