Generation and Characterization of Rat Monoclonal Antibodies Against Epidermal Growth Factor Receptor

Overexpression of the epidermal growth factor receptor (EGFR) gene and dysregulation of EGFR signaling are observed in various cancer cells, and EGFR is a validated target for cancer therapy. In the present study, we report on the generation of two rat anti-EGFR antibodies (clones 2C2D3 and 4H7F4) b...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Monoclon Antib Immunodiagn Immunother
Prif Awduron: Osaki, Tomohiro, Wang, Cai-Xia, Tachibana, Taro, Azuma, Masayuki, Kitamura, Masaya, Nakanishi, Takeshi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc. 2015
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685498/
https://ncbi.nlm.nih.gov/pubmed/26683181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/mab.2015.0034
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