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Generation and Characterization of a New Monoclonal Antibody Against CXCL4

CXCL4 plays important roles in numerous disease processes, which makes the CXCL4 signaling pathway a potential therapeutic target. In this study, we aimed to develop a neutralizing antibody against both human and mouse CXCL4. Rats were immunized with recombinant human CXCL4 (rhCXCL4). Hybridoma clon...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Monoclon Antib Immunodiagn Immunother
Hauptverfasser: Gao, Jing, Wu, Mingyuan, Gao, Jin, Wang, Xia, Zhang, Yang, Zhu, Shunying, Yu, Yan, Han, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410284/
https://ncbi.nlm.nih.gov/pubmed/25897609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/mab.2014.0050
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