Activation of p38-MAPK by CXCL4/CXCR3 axis contributes to p53-dependent intestinal apoptosis initiated by 5-fluorouracil

Chemotherapy-induced mucositis (CIM) is a major does limiting side-effect of chemoagents such as 5-fluorouracil (5-FU). Molecules involved in this disease process are still not fully understood. We proposed that the homeostatically regulated genes during CIM may participate in the disease. A cluster...

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Hlavní autoři: Gao, Jing, Gao, Jin, Qian, Lan, Wang, Xia, Wu, Mingyuan, Zhang, Yang, Ye, Hao, Zhu, Shunying, Yu, Yan, Han, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2014
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Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119083/
https://ncbi.nlm.nih.gov/pubmed/24800927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.29114
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