p38 MAPK regulates Bax activity and apoptosis in enterocytes at baseline and after intestinal resection

Increased apoptosis in crypt enterocytes is a key feature of intestinal adaptation following massive small bowel resection (SBR). Expression of the proapoptotic factor Bax has been shown to be required for resection-induced apoptosis. It has also been demonstrated that p38-α MAPK (p38) is necessary...

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Hlavní autoři: Wakeman, Derek, Guo, Jun, Santos, Jethrina A., Wandu, Wambui S., Schneider, John E., McMellen, Mark E., Leinicke, Jennifer A., Erwin, Christopher R., Warner, Brad W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2012
Témata:
Mucosal Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362074/
https://ncbi.nlm.nih.gov/pubmed/22383494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00485.2011
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