Heterogeneity of glucagonomas due to differential processing of proglucagon-derived peptides

Pancreatic neuroendocrine tumours (pNETs) secreting proglucagon are associated with phenotypic heterogeneity. Here, we describe two patients with pNETs and varied clinical phenotypes due to differential processing and secretion of proglucagon-derived peptides (PGDPs). Case 1, a 57-year-old woman pre...

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Bibliografski detalji
Izdano u:Endocrinol Diabetes Metab Case Rep
Glavni autori: Challis, Benjamin G, Albrechtsen, Nicolai J Wewer, Bansiya, Vishakha, Burling, Keith, Barker, Peter, Hartmann, Bolette, Gribble, Fiona, O'Rahilly, Stephen, Holst, Jens J, Simpson, Helen L
Format: Artigo
Jezik:Inglês
Izdano: Bioscientifica Ltd 2015
Teme:
Insight into Disease Pathogenesis or Mechanism of Therapy
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685488/
https://ncbi.nlm.nih.gov/pubmed/26693280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EDM-15-0105
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