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The molecular mechanism of photochemical internalization of cell penetrating peptide-cargo-photosensitizer conjugates

In many drug delivery strategies, an inefficient transfer of macromolecules such as proteins and nucleic acids to the cytosol often occurs because of their endosomal entrapment. One of the methods to overcome this problem is photochemical internalization, which is achieved using a photosensitizer an...

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Foilsithe in:Sci Rep
Main Authors: Ohtsuki, Takashi, Miki, Shunya, Kobayashi, Shouhei, Haraguchi, Tokuko, Nakata, Eiji, Hirakawa, Kazutaka, Sumita, Kensuke, Watanabe, Kazunori, Okazaki, Shigetoshi
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2015
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685267/
https://ncbi.nlm.nih.gov/pubmed/26686907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18577
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