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The molecular mechanism of photochemical internalization of cell penetrating peptide-cargo-photosensitizer conjugates

In many drug delivery strategies, an inefficient transfer of macromolecules such as proteins and nucleic acids to the cytosol often occurs because of their endosomal entrapment. One of the methods to overcome this problem is photochemical internalization, which is achieved using a photosensitizer an...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ohtsuki, Takashi, Miki, Shunya, Kobayashi, Shouhei, Haraguchi, Tokuko, Nakata, Eiji, Hirakawa, Kazutaka, Sumita, Kensuke, Watanabe, Kazunori, Okazaki, Shigetoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685267/
https://ncbi.nlm.nih.gov/pubmed/26686907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18577
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