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A regulated, ubiquitin-independent degron in IκBα
Whereas ubiquitin-dependent degrons have been characterized in some detail, how proteins may be targeted to ubiquitin-independent proteasomal degradation remains unclear. Here we show that IκBα contains a ubiquitin-independent degron whose activity is portable to heterologous proteins such as the gl...
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| Publié dans: | J Mol Biol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4685248/ https://ncbi.nlm.nih.gov/pubmed/26191773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.07.008 |
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