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A cGAS-independent STING-IRF7 pathway mediates the immunogenicity of DNA vaccines()

It is known since the discovery of DNA vaccines more than 20 years ago that DNA vaccines can function as adjuvants. Our recent study reported the involvement of Aim2 as the sensor of DNA vaccines in eliciting antigen-specific antibody responses. Our findings indicated the presence of previously unre...

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Vydáno v:J Immunol
Hlavní autoři: Suschak, John, Wang, Shixia, Fitzgerald, Katherine A., Lu, Shan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685033/
https://ncbi.nlm.nih.gov/pubmed/26590319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501836
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