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Migration of CD8+ T cells into the CNS gives rise to highly potent anti-HIV CD4(dim)CD8(bright) T cells in a Wnt signaling -dependent manner

The role of CD8+ T cells in HIV control in the brain and the consequences of such control are unclear. Approximately 3% of peripheral CD8(+) T cells dimly express CD4 on their surface. This population is known as CD4(dim)CD8(bright) T cells. We evaluated the role of CD4(dim)CD8(bright) and CD8 singl...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Richards, Maureen H., Narasipura, Srinivas D., Seaton, Melanie S., Lutgen, Victoria, Al-Harthi, Lena
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685022/
https://ncbi.nlm.nih.gov/pubmed/26582945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501394
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