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Porcupine Is Not Required for the Production of the Majority of Wnts from Primary Human Astrocytes and CD8+ T Cells

Wnts are small secreted glycoproteins that are highly conserved among species. To date, 19 Wnts have been described, which initiate a signal transduction cascade that is either β-catenin dependent or independent, culminating in the regulation of hundreds of target genes. Extracellular release of Wnt...

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Detalhes bibliográficos
Main Authors: Richards, Maureen H., Seaton, Melanie S., Wallace, Jennilee, Al-Harthi, Lena
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960167/
https://ncbi.nlm.nih.gov/pubmed/24647048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092159
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