IL-36 receptor promotes resolution of intestinal damage

Interleukin-1 family members are central mediators of host defense. Here we show that the novel IL-1 family member, IL-36γ, was expressed during experimental colitis and human inflammatory bowel disease (IBD). In response to dextran sodium sulfate (DSS)-induced damage, germ-free (GF) mice failed to...

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Udgivet i:J Immunol
Main Authors: Medina-Contreras, Oscar, Harusato, Akihito, Nishio, Hikaru, Flannigan, Kyle L., Ngo, Vu, Leoni, Giovanna, Neumann, Philipp-Alexander, Geem, Duke, Lili, Loukia N., Ramadas, Ravisankar A., Chassaing, Benoit, Gewirtz, Andrew T., Kohlmeier, Jacob E., Parkos, Charles A., Towne, Jennifer E., Nusrat, Asma, Denning, Timothy L.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684965/
https://ncbi.nlm.nih.gov/pubmed/26590314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501312
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