Evolutionary context for the association of γ-globin, serum uric acid, and hypertension in African Americans

BACKGROUND: Hyperuricemia and associated cardio-metabolic disorders are more prevalent in African Americans than in European Americans. We used genome-wide admixture mapping and association testing to identify loci with ancestry effects on serum uric acid levels. METHODS: We analyzed 1,976 African A...

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發表在:BMC Med Genet
Main Authors: Shriner, Daniel, Kumkhaek, Chutima, Doumatey, Ayo P., Chen, Guanjie, Bentley, Amy R., Charles, Bashira A., Zhou, Jie, Adeyemo, Adebowale, Rodgers, Griffin P., Rotimi, Charles N.
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684912/
https://ncbi.nlm.nih.gov/pubmed/26686224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-015-0249-z
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