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Tissue and urokinase plasminogen activators instigate the degeneration of retinal ganglion cells in a mouse model of glaucoma

Elevated intraocular pressure (IOP) promotes the degeneration of retinal ganglion cells (RGCs) during the progression of Primary Open-Angle Glaucoma (POAG). However, the molecular mechanisms underpinning IOP-mediated degeneration of RGCs remain unclear. Therefore, by employing a mouse model of POAG,...

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Détails bibliographiques
Publié dans:Exp Eye Res
Auteur principal: Chintala, Shravan K
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684789/
https://ncbi.nlm.nih.gov/pubmed/26474495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2015.10.003
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