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Inhibition of Plasminogen Activators Attenuates the Death of Differentiated Retinal Ganglion Cells and Stabilizes Their Neurite Network In Vitro

PURPOSE: Although previous studies have indicated that elevated levels of the tissue plasminogen activator (tPA) and the urokinase plasminogen activator (uPA) associate with the death of retinal ganglion cells (RGCs), it was unclear whether these proteases directly cause cell death. With the use of...

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Detalhes bibliográficos
Main Authors: Harvey, Ronée, Chintala, Shravan K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884129/
https://ncbi.nlm.nih.gov/pubmed/17389524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.06-0990
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