Germline Genetic Variation in ETV6 and Risk of Childhood Acute Lymphoblastic Leukemia: a Systematic Genetic Study

BACKGROUND: Hereditary predisposition is rarely suspected for childhood acute lymphoblastic leukemia (ALL). Recent studies identified germline ETV6 variations associated with marked familial clustering of hematologic malignancies, pointing to this gene as a potentially important genetic determinant...

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Publicado en:Lancet Oncol
Autores principales: Moriyama, Takaya, Metzger, Monika L., Wu, Gang, Nishii, Rina, Qian, Maoxiang, Devidas, Meenakshi, Yang, Wenjian, Cheng, Cheng, Cao, Emily, Quinn, Raimondi, Susana, Gastier-Foster, Julie M., Raetz, Elizabeth, Larsen, Eric, Martin, Paul L., Bowman, W. Paul, Winick, Naomi, Komada, Yoshihiro, Wang, Shuoguo, Edmonson, Michael, Xu, Heng, Mardis, Elaine, Fulton, Robert, Pui, Mullighan, Charles, Evans, William E., Zhang, Jinghui, Hunger, Stephen P., Relling, Mary V., Nichols, Kim E., Loh, Mignon L., Yang, Jun J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684709/
https://ncbi.nlm.nih.gov/pubmed/26522332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(15)00369-1
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