Molecular basis of ETV6-mediated predisposition to childhood acute lymphoblastic leukemia

There is growing evidence supporting an inherited basis for susceptibility to acute lymphoblastic leukemia (ALL) in children. In particular, we and others reported recurrent germline ETV6 variants linked to ALL risk, which collectively represent a novel leukemia predisposition syndrome. To understan...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Nishii, Rina, Baskin-Doerfler, Rebekah, Yang, Wentao, Oak, Ninad, Zhao, Xujie, Yang, Wenjian, Hoshitsuki, Keito, Bloom, Mackenzie, Verbist, Katherine, Burns, Melissa, Li, Zhenhua, Lin, Ting-Nien, Qian, Maoxiang, Moriyama, Takaya, Gastier-Foster, Julie M., Rabin, Karen R., Raetz, Elizabeth, Mullighan, Charles, Pui, Ching-Hon, Yeoh, Allen Eng-Juh, Zhang, Jinghui, Metzger, Monika L., Klco, Jeffery M., Hunger, Stephen P., Newman, Scott, Wu, Gang, Loh, Mignon L., Nichols, Kim E., Yang, Jun J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2021
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7819760/
https://ncbi.nlm.nih.gov/pubmed/32693409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020006164
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